Publications

	[29]	C. Rieder, M. Schwenke, T. Pätz, J. Georgii, H. Ballhausen, L. O. Schwen, S. Haase, and T. Preusser: Evaluation of a numerical simulation for cryoablation – comparison with bench data, clinical kidney and lung cases International Journal of Hyperthermia 37(1): 1268–1278, 2020. [article (open access) \| bib \| abstract ]
	[28]	J. Georgii, T. Pätz, C. Rieder, H. Ballhausen, M. Schwenke, L. O. Schwen, S. Haase, and T. Preusser: Efficient GPU-Based Numerical Simulation of Cryoablation of the Kidney In: K. Miller, A. Wittek, G. Joldes, M. P. Nash, and P. M. F. Nielsen: Computational Biomechanics for Medicine. MICCAI 2019, MICCAI 2018, 171–193, Springer 2020. [article \| bib \| abstract ]
	[27]	L. O. Schwen^☯, E. Andersson^☯, K. Korski, N. Weiss, S. Haase, F. Gaire, H. K. Hahn, A. Homeyer^☯, and O. Grimm^☯: Data-Driven Discovery of Immune Contexture Biomarkers Frontiers in Oncology 8(627): 1–15, 2018. [article (open access) \| bib \| abstract ]
	[26]	L. O. Schwen^☯ and S. Rueschenbaum^☯: Ten Quick Tips for Getting the Most Scientific Value out of Numerical Data PLOS Computational Biology 14(10): 1–21, 2018. [article (open access) \| bib \| abstract \| erratum ]
	[25]	A. Homeyer, S. Hammad, L. O. Schwen, U. Dahmen, H. Höfener, Y. Gao, S. Dooley, and A. Schenk: Focused scores enable reliable discrimination of small differences in steatosis Diagnostic Pathology 13(76): 1–9, 2018. [article (open access) \| bib \| abstract]
	[24]	L. O. Schwen, L. Kuepfer, and T. Preusser: Modeling Approaches for Hepatic Spatial Heterogeneity in Pharmacokinetic Simulations Drug Discovery Today: Disease Models 22, 2016, 35–43, 2017. [article \| preprint (pdf) \| bib \| abstract]
	[23]	B. Christ^☯, U. Dahmen^☯, K.-H. Herrmann^☯, M. König^☯, J. Reichenbach^☯, T. Ricken^☯, J. Schleicher^☯, L. O. Schwen^☯, S. Vlaic^☯, and N. Waschinsky^☯α: Computational Modeling in Liver Surgery Frontiers in Physiology, Gastrointestinal Sciences 8, 906, 2017. [article (open access) \| preprint (pdf) \| bib \| abstract]
	[22]	A. Schenk, A. Ghallab, U. Hofmann, R. Hassan, M. Schwarz, A. Schuppert, L. O. Schwen, A. Braeuning, D. Teutonico, J. G.. Hengstler, and L. Kuepfer: Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage Scientific Reports 7: 6224, 1–13, 2017. [article (open access) \| preprint (pdf) \| bib \| abstract]
	[21]	C. Xie, W. Wei, A. Schenk, L. O. Schwen, S. Zafarnia, M. Schwier, F. Gremse, I. Jank, O. Dirsch, and U. Dahmen: Visualization of Vascular and Parenchymal Regeneration After 70% Partial Hepatectomy in Normal Mice Journal of Visualized Experiments, 115: e53935, 1–6, 2016. [article \| video \| preprint (pdf) \| bib \| abstract]
	[20]	C. Xie, L. O. Schwen, W. Wei, A. Schenk, S. Zafarnia, F. Gremse, and U. Dahmen: Quantification of Hepatic Vascular and Parenchymal Regeneration in Mice PLoS ONE, 11(8): e0160581, 1–19, 2016. [article (open access) \| preprint (pdf) \| supporting information \| bib \| abstract]
	[19]	L. O. Schwen, A. Homeyer, M. Schwier, U. Dahmen, O. Dirsch, A. Schenk, L. Kuepfer, T. Preusser, and A. Schenk: Zonated Quantification of Steatosis in an Entire Mouse Liver Computers in Biology and Medicine, 73, 108–118, 2016. [article \| preprint (pdf) \| bib \| abstract]
	[18]	C. Sänger, A. Schenk, L. O. Schwen, L. Wang, S. Zafarnia, F. Kiessling, C. Xie, W. Wei, B. Richter, O. Dirsch, and U. Dahmen: Intrahepatic Vascular Anatomy in Rats and Mice—Variations and Surgical Implications PLoS ONE, 10(11):e0141798, 1–13, 2015. [article (open access) \| preprint (pdf) \| bib \| abstract]
	[17]	L. O. Schwen, T. Pätz, and T. Preusser: Some Use Cases for Composite Finite Elements in Image Based Computing. In G. R. Joldes, B. Doyle, A. Wittek, P. M. F. Nielsen, and K. Miller: Computational Biomechanics for Medicine, 117–129, Springer, 2016. (Proceedings of MICCAI 2015 Workshop Computational Biomechanics for Medicine X) [chapter \| preprint (pdf) \| bib \| abstract]
	[16]	L. O. Schwen, A. Schenk, C. Kreutz, J. Timmer, M. M. Bartolomé-Rodríguez, L. Kuepfer, and T. Preusser: Representative Sinusoids For Hepatic Four-Scale Pharmacokinetics Simulations PLoS ONE, 10(7):e0133653, 1–39, 2015. [article (open access) \| preprint (pdf) \| supporting information \| bib \| abstract]
	[15]	F. Gremse, A. Höfter, L. O. Schwen, F. Kiessling, and U. Naumann: GPU-Accelerated Sparse Matrix-Matrix Multiplication by Iterative Row Merging. SIAM Journal on Scientific Computing, 37(1), C54–C71, 2015. [article \| preprint (pdf) \| bib \| abstract]
	[14]	L. O. Schwen, W. Wei, F. Gremse, J. Ehling, L. Wang, U. Dahmen, and T. Preusser: Algorithmically Generated Rodent Hepatic Vascular Trees in Arbitrary Detail. Journal of Theoretical Biology, 365, 289–300, 2015. [article (open access) \| preprint (pdf) \| supporting information \| bib \| abstract]
	[13]	L. O. Schwen, M. Krauss, C. Niederalt, F. Gremse, F. Kiessling, A. Schenk, T. Preusser, and L. Kuepfer: Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver. PLOS Computational Biology, 10(3), e1003499, 2014. [article (open access) \| preprint (pdf) \| supporting information \| bib \| abstract]
	[12]	L. O. Schwen and U. Wolfram^α: Validation of Composite Finite Elements Efficiently Simulating Elasticity of Trabecular Bone. Computer Methods in Biomechanics and Biomedical Engineering, 17(6), 652–660, 2014. [article \| preprint (pdf) \| bib \| abstract] ^αalphabetical author list
	[11]	L. O. Schwen and T. Preusser: Analysis and Algorithmic Generation of Hepatic Vascular Systems. International Journal of Hepatology, Article ID 357687, 1–17, 2012. [article (open access) \| preprint (pdf) \| bib \| abstract]
	[10]	L. O. Schwen, T. Pätz, and T. Preusser: Composite Finite Element Simulation of Radio Frequency Ablation and Bone Elasticity. Proceedings of 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012), ISBN 978-3-9502481-9-7. [preprint (pdf) \| bib \| abstract]
	[9]	T. Preusser, M. Rumpf, S. Sauter, and L. O. Schwen^α: 3D composite finite elements for elliptic boundary value problems with discontinuous coefficients. SIAM Journal on Scientific Computing, 33(5), 2115–2143, 2011. [article \| preprint (pdf) \| bib \| abstract] ^αalphabetical author list
	[8]	M. Rumpf, L. O. Schwen, H.-J. Wilke, and U. Wolfram^α: Numerical homogenization of trabecular bone specimens using composite finite elements. In The International Journal of Multiphysics, Special Edition: Multiphysics Simulations – Advanced Methods for Industrial Engineering. Selected Contributions from 1st Fraunhofer Multiphysics Conference, 127–143. Fraunhofer, Multi-Science Publishing, 2010, ISBN 978-1-907132-36-0. [preprint (pdf) \| bib \| abstract] ^αalphabetical author list
	[7]	L. O. Schwen: Composite Finite Elements for Trabecular Bone Microstructures. Dissertation, University of Bonn, 2010. HARLAND media, ISBN 978-3-938363-78-2. [dissertation (open access) \| book \| pdf \| bib \| abstract]
	[6]	U. Wolfram^☯, L. O. Schwen^☯, U. Simon, M. Rumpf, and H.-J. Wilke: Statistical osteoporosis models using composite finite elements: A parameter study. Journal of Biomechanics, 42(13), 2205–2209, September 2009. [article \| preprint (pdf) \| bib \| abstract]
	[5]	F. Liehr, T. Preusser, M. Rumpf, S. Sauter, and L. O. Schwen^α: Composite finite elements for 3D image based computing. Computing and Visualization in Science, 12(4), 171–188, April 2009. [article \| preprint (pdf) \| bib \| abstract] ^αalphabetical author list
	[4]	L. O. Schwen, T. Preusser, and M. Rumpf: Composite finite elements for 3D elasticity with discontinuous coefficients. In Proceedings of the 16th Workshop on the Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields. University of Ulm, 2009. [preprint (pdf) \| bib \| abstract]
	[3]	L. O. Schwen, U. Wolfram, H.-J. Wilke, and M. Rumpf. Determining effective elasticity parameters of microstructured materials. In Proceedings of the 15th Workshop on the Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields, 41–62. University of Ulm, July 2008. [preprint (pdf) \| bib \| abstract]
	[2]	T. Preusser, M. Rumpf, and L. O. Schwen^α: Finite element simulation of bone microstructures. In Proceedings of the 14th Workshop on the Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields, 52–66. University of Ulm, July 2007, ISBN 978-3-9806183-9-7. [preprint (pdf) \| bib \| abstract] ^αalphabetical author list
	[1]	L. O. Schwen: Numerical simulation of transport and diffusion in drainage media. Diplom thesis, Duisburg-Essen University, 2005. [thesis (pdf) (open access) \| bib \| abstract]
		^☯shared first authorship ^αalphabetical author list

Conferences and External Presentations

2020-09 ESMO Virtual Congress 2020: AI-Based Grading Approach Identifies FNCLCC Grade 3 Soft Tissue Sarcomas [poster] (co-authored) [abstract | bib]
2018-07-04 Bremen, SBMC 2018: Integration of Representative Sinusoids into a Physiologically Based Whole-Body Model for a Detailed Description of Biliary Transport [poster] [video]
2016-09-09 Magdeburg, 20. Chirurgische Foschungstage: Zonated Quantification of Steatosis for Pharmacokinetics Simulations [slides] [video] [abstract]
2015-10-05 Munich, MICCAI Workshop Computational Biomechanics for Medicine X: Some Use Cases for Composite Finite Elements in Image Based Computing [poster]
2014-11-20 Jena, JCB Seminar: Multi-Scale Simulation of Heterogeneous Metabolism in Mammalian Livers [slides] [video] [video]
2014-09-10 Trondheim, VPH 2014: Multiscale Simulation of Zonated Metabolism in Steatotic Livers [slides] [video] [abstract]
2014-09-04 Durham (UK), ISGSB 2014: Spatio-Temporal Simulation of First Pass Drug Perfusion in a Murine Liver [slides] [video]
2014-07-21 Barcelona, WCCM-ECCM-ECFD 2014: Spatially Resolved Simulation of Glucose Metabolism in the Human Liver [slides] [video] [abstract]
2014-05-14 Berlin, SBMC 2014: Multi-Scale Simulation of Zonated Liver Metabolism [slides] [talk]
2014-02-28 Jacobs University Bremen, Lecture Series on Reductionism in Physics and its Relation to Philosophy: Multiscale Elasticity Modeling of Trabecular Bone [slides]
2013-11-22 Institute for Surgical Technology and Biomechanics, University of Bern: Composite FE for Image-Based Simulations—Construction and Applications [slides]
2013-03-08 Jacobs University Bremen, Lecture Series on Reductionism in Physics and its Relation to Philosophy: Multiscale Elasticity Modeling of Trabecular Bone [slides]
2013-02: Modelling Drug Distribution in the Liver (Video on vimeo.com by the Virtual Liver Network): [video]
2012-11-22 Universität Zurich, Seminar über Partielle Differentialgleichungen und Numerik: Composite Finite Elements for Image-Based Simulations—Construction and Applications [slides]
2012-09-13 Vienna, ECCOMAS 2012: Composite Finite Element Simulation of Radio Frequency Ablation and Bone Elasticity [slides]
2012-08-23 Berlin, ISMP 2012: Modeling Flow Through Realistic, Algorithmically Generated Vascular Structures in the Liver [slides] [video]
2011-06-29 Krakow, ECMTB 2011: Constructive Algorithms for Modeling Realistic Vascular Structures [slides]
2010-08-20 Jacobs University Bremen, Heraeus Workshop on Biomedical Modeling and Visualization: Composite Finite Elements for Numerical Homogenization of Trabecular Bone Specimens [slides]
2010-06-22 Bonn, Fraunhofer Conference on Multiphysics Simulation: Numerical Homogenization of Trabecular Bone Specimens using Composite Finite Elements [slides]
2009-07-15 Ulm, Finite Element Workshop: Composite Finite Elements for Discontinuous Coefficients [slides]
2008-07-16 Ulm, Finite Element Workshop: Determining Effective Elasticity Parameters of Microstructured Materials [slides]
2007-11-15 Bremen, CeVis: Multigrid Methods for Complicated Domains [slides]
2007-07-18 Ulm, Finite Element Workshop: CFE for Image Based Computing [slides] [poster]
2007-03-23 Darmstadt: CFE for Image Based Computing [slides]
2006-09-22 Ulm: UFB Research Club: Composite Finite Elements [slides]
2006-01-11 Bremen, MeVis: Numerical Simulation of Transport and Diffusion in Drainage Media [slides]

Teaching and Internal Seminars

2018-10-23 Bremen, MEVIS Oberseminar: Tips & Tricks for Getting the Most Value out of Numerical Data [slides], previous version presented on 2017-09-13 at CdE Biomodels Retreat 2017, Caldes d’Estrac/Barcelona [slides]
2015-09-02 Bremen, MEVIS Developer Seminar: Using the Standard Template Library (STL) [slides + example code]
2015-05-22 Bremen, MEVIS Academy: A ~~Penguin~~ Practical Introduction to Ordinary Differential Equations [slides + example code]
2014-10/11 Jacobs University Bremen, Symbolic Software Lab, 2 lectures on LaTeX [lecture 1] [lecture 2]
2014-03-21 Bremen, MEVIS Academy: How to Avoid an Ugly Presentation of Your Excellent Results: An Introduction to Typography [slides]
2013-12-08 Weimar, CdE-Seminar, Spatio-Temporal Simulation of First Pass Drug Perfusion in the Mouse Liver [slides] [video] (previously presented at MEVIS Oberseminar, Bremen 2013-09-17 [slides])
2013-11/12 Jacobs University Bremen, Symbolic Software Lab, 2 lectures on LaTeX [lecture 1] [lecture 2]
2013-10-26 Hünfeld, 3rd Virtual Liver Retreat, Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver [poster] [video]
2012-11-28 Hünfeld, 2nd Virtual Liver Retreat: A Spatio-Temporally Resolved Hepatic Pharmacokinetics Model [slides] [video]
2010-11-27 Siegburg, CdE-Seminar: Composite Finite Elements for Jumping Coefficients Composite Finite Elements for Numerical Homogenization of Trabecular Bone Specimens [slides]
2010-10-07 Bonn, Promotionskolloquium: Zusammengesetzte Finite Elemente für trabekuläre Mikrostrukturen [slides]
2008-11-08 Siegburg, CdE-Seminar: Composite Finite Elements for Jumping Coefficients [slides]
2008-07-03 Bonn, Geodätisches Integrations-Seminar: Multiscale Computing for Microstructured Objects [slides]
2008-05-08 Bonn, Oberseminar INS: Cell Problems for Elastic Microstructures [slides]
2007-12-01 Siegburg, CdE-Seminar: Multigrid Methods for Complicated Domains [slides]
2007-01-24 DDK: CFE [slides]
2006-11-11 Siegburg: CdE-Seminar: CFE [slides]
2006-01-26 Bonn: Oberseminar INS: Diplomarbeit [slides]
2005-12-03 Darmstadt: CdE-Seminar: Diplomarbeit [slides]
2005-05-09 Bonn: Oberseminar INS: ELLAM [slides]
2004-05-06 Seattle: Numerical Analysis Reading Club: Multigrid Methods [slides]

	Dr. rer. nat. Lars Ole Schwen
E-mail
Address	Fraunhofer MEVIS Am Fallturm 1 D-28359 Bremen
Phone	+49 421 218 59275
Fax	+49 421 218 98 59275
Find me on	Google scholar \| ResearchGate \| ORCID \| Publons

Contact

Research Topics

Publications

Conferences and External Presentations

Teaching and Internal Seminars